[HTML][HTML] QSAR analysis of benzophenone derivatives as antimalarial agents
S Mahajan, V Kamath, S Nayak… - Indian Journal of …, 2012 - ncbi.nlm.nih.gov
A set of benzophenone derivatives was evaluated for the antimalarial activity against
Plasmodium berghei in mice and the mean survival time of mice for all the compounds was
determined. The QSAR analysis was carried out for the fourteen benzophenone derivatives
using different physicochemical descriptors. The multiple linear regression analysis was
used to correlate the physicochemical descriptors with the antimalarial activity of the
benzophenone derivatives from the training set and the best QSAR model was developed …
Plasmodium berghei in mice and the mean survival time of mice for all the compounds was
determined. The QSAR analysis was carried out for the fourteen benzophenone derivatives
using different physicochemical descriptors. The multiple linear regression analysis was
used to correlate the physicochemical descriptors with the antimalarial activity of the
benzophenone derivatives from the training set and the best QSAR model was developed …
QSAR analysis of benzophenone derivatives as antimalarial agents.
SM Supriya Mahajan, VK Vijayalaxmi Kamath… - 2012 - cabidigitallibrary.org
A set of benzophenone derivatives was evaluated for the antimalarial activity against
Plasmodium berghei in mice and the mean survival time of mice for all the compounds was
determined. The QSAR analysis was carried out for the fourteen benzophenone derivatives
using different physicochemical descriptors. The multiple linear regression analysis was
used to correlate the physicochemical descriptors with the antimalarial activity of the
benzophenone derivatives from the training set and the best QSAR model was developed …
Plasmodium berghei in mice and the mean survival time of mice for all the compounds was
determined. The QSAR analysis was carried out for the fourteen benzophenone derivatives
using different physicochemical descriptors. The multiple linear regression analysis was
used to correlate the physicochemical descriptors with the antimalarial activity of the
benzophenone derivatives from the training set and the best QSAR model was developed …
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